Configuring Business Units (OBS)
Business units can be defined as a way of classifying large organizations into smaller units that are related to one another. Sorting related areas into units makes it easier to determine whether or not certain units are profitable and should be continued.

Configure System
Setup System-wide preferences, Security, User Defined Fields and Automation.

Configure Sites
Setup Currency, Holiday and Regional Settings.

Configure Business Units*
Setup Business Units and associate with Projects/Users

Configure Resource Types
Create a Resource Type and setup Overtime Policy as well as Leave Time.

Configure Groups
Setup Work Types, Leave Time, Business Unit Association and Approvers. Manage Members.

Configure Teams*
Setup Teams and Team Members.

Configure Titles*

Configure Roles*
Role Definition, Members and Forecast Rates.

Configure Users
Setup Users. Site and Group Association, Contact, Login Information & Security Profile, Holiday Set, Resource Type Association and Cost & Billing Rules.
Note: * Business Unit, Team, Title and Role Setup are optional.
The article listed here will help guide you through the process of setting up the Business Units in PSA: